By Charles J. Hackett, Donald A. Harn Jr
A state-of-the-art assessment of the key learn parts of adjuvant discovery, layout, improvement, and use. The authors lay down a rational foundation for vaccine adjuvant functionality and study a few considerably exact adjuvant-active molecules to light up the rules in their functionality and use. the point of interest is on particular receptor-ligand interactions, together with the molecular positive aspects wanted for a compound to own adjuvant task. The serious interface region among the innate and adaptive immune platforms can also be analyzed to teach how adjuvants exert their results on T- and B-cell activation. extra chapters handle the potential for tailoring adjuvants to yield optimally secure and powerful responses.
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Vaccine Adjuvants: Immunological and Clinical Principles (Infectious Disease) by Charles J. Hackett, Donald A. Harn Jr