Download PDF by Douglas Hanahan, Robert A. Weinberg: The Hallmarks of Cancer

By Douglas Hanahan, Robert A. Weinberg

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Corbalan-Garcia, S. (2001). Identification of the Phosphatidylserine Binding Site in the C2 Domain that Is Important for PKCalpha Activation and in Vivo Cell Localization. Biochemistry, 40(46), 13898–13905. C. (2007). The C2 domains of classical/conventional PKCs are specific PtdIns(4,5)P(2)-sensing domains. Biochemical Society Transactions, 35(Pt 5), 1046–1048. C. (2007). A single residue in the C1 domain sensitizes novel protein kinase C isoforms to cellular diacylglycerol production. The Journal Biologica Chemistry, 282(2), 826–830.

Biochemistry, 37(35), 12020–12025. , Wong. , et al. (1994). Zinc Finger Domains and Phorbol Ester Pharmacophore: Analysis of binding to mutated form of protein kinase C z and the vav and c-raf proto-oncogene products. The Journal Biological Chemistry, 269, 11590–11594. C. C. (1995). Protein kinase C is regulated in vivo by three functionally distinct phosphorylations. Current Biology, 5(12), 1394–1403. , et al (2003). Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.

2008). The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail. The Journal of Biological Chemistry, 284(8), 4921–4835. C. (2008). The life and death of protein kinase C. Current Drug Targets, 9(8), 614–625. G. (2007). Protein kinase C and other diacylglycerol effectors in cancer. Nature Reviews. Cancer, 7(4), 281–294. , et al. (2006). Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.

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The Hallmarks of Cancer by Douglas Hanahan, Robert A. Weinberg

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