By Nancy J. Wesensten
Sleep Deprivation: Stimulant medicines and Cognition offers a evaluate, synthesis and research of the medical literature relating stimulant drugs and neurobehavioral functionality, with an emphasis on severely comparing the sensible software of those brokers for keeping cognitive functionality and application in sleep-deprived (but another way fit) contributors. The booklet explores the character of sleep loss-induced cognitive deficits, neurophysiologic foundation of those deficits, relative efficacy and boundaries of varied interventions (including non-pharmacological), and implications for employing those interventions in operational environments (commercial and military). Readers of this quantity will achieve a operating wisdom of: • Mechanisms contributing to sleep loss-induced cognitive deficits; • Differential results of stimulant compounds on a number of elements of cognition; • issues (e.g., abuse legal responsibility) while employing stimulant interventions in operational settings; • present kingdom and destiny instructions for together with stimulants in accomplished fatigue-management innovations. this article is essential examining for researchers and trainees in sleep and psychopharmacology
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Additional info for Sleep deprivation, stimulant medications, and cognition
82] Chuah LY, Chong DL, Chen AK, et al. Donepezil improves episodic memory in young individuals vulnerable to the effects of sleep deprivation. Sleep 2009; 32(8): 999–1010.  Vandewalle G, Archer SN, Wuillaume C, et al. Functional magnetic resonance imaging-assessed brain responses during an executive task depend on interaction of sleep homeostasis, circadian phase, and PER3 genotype. J Neurosci 2009; 29(25): 7948–56.  Schmidt C, Collette F, Leclercq Y, et al. Homeostatic sleep pressure and responses to sustained attention in the suprachiasmatic area.
Section 1 Basic Mechanisms: Cognitive Performance and Sleep Chapter Neurochemistry of wakefulness and sleep 3 Robert E. Strecker and James T. McKenna Introduction Akin to nutrition and exercise, sleep is necessary for optimal daytime cognitive and behavioral performance. Conversely, inadequate sleep impairs human performance on a wide variety of cognitive and behavioral tasks, leading to increased accident rates and decreased efﬁciency at work and school (reviewed in ). Sleep loss is now considered a major public safety and health concern [2, 3].
44] Bell-McGinty S, Habeck C, Hilton HJ, et al. Identiﬁcation and differential vulnerability of a neural network in sleep deprivation. Cereb Cortex 2004; 14(5): 496–502. 20  Cajochen C, Brunner DP, Krauchi K, Graw P, WirzJustice A. Power density in theta/alpha frequencies of the waking EEG progressively increases during sustained wakefulness. Sleep 1995; 18(10): 890–4.  Lim J, Tan JC, Parimal S, Dinges DF, Chee MW. Sleep deprivation impairs object-selective attention: a view from the ventral visual cortex.
Sleep deprivation, stimulant medications, and cognition by Nancy J. Wesensten