Prostate Cancer (Deadly Diseases and Epidemics) - download pdf or read online

By Scott Cramer

ISBN-10: 0791089355

ISBN-13: 9780791089354

ISBN-10: 1438101627

ISBN-13: 9781438101620

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Bostwick, Pathology of the Prostate. B. Saunders, 1998. PSA test. If the results are still abnormal the next year, and especially if the test results are worse, then another biopsy will be performed at that time. STAGING THE CANCER If cancer is found, then the course of action for treatment depends on the determination of how aggressive the cancer is. Staging refers to the process of determining the degree that the prostate cancer has spread through the prostate gland and to other parts of the body.

A phase III trial is designed to test a hypothesis so that definite conclusions can be drawn. gov/clinicaltrials. C04_P3 54 3/5/08 5:25 PM Page 54 PROSTATE CANCER versus what a prostate cancer nodule feels like. It may also be helpful to have the same doctor perform the DRE each year, so that he or she is familiar with what the prostate felt like at the last examination. The DRE screening test does not provide a diagnosis for prostate cancer—this can only come from looking at the pathology of the prostate, usually from a sample taken by needle biopsy—but it has the major advantage of being quick, easy, and inexpensive.

Extensive preclinical testing is done before conducting a clinical trial in humans. These preclinical tests will often include laboratory studies in animal and human cell culture (see sidebar in chapter 2) and in animal models of the disease (see sidebar in chapter 3). There are three phases of clinical trials. Phase I trials: These first human studies are designed to test safety and methods of administration. Usually only a few people are enrolled in a phase I trial. Phase II trials: A phase II trial continues to test the safety of the drug, and begins to evaluate how well the new drug works.

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Prostate Cancer (Deadly Diseases and Epidemics) by Scott Cramer

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