By Samir A. Farghaly
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Extra resources for Ovarian Cancer -Clinical Therapeutic Perspectives
Cancer 2007;109:221-7.  Goff BA, Mandel LS, Melancon CH, Muntz HG. Frequency of symptoms of ovarian cancer in women presenting to primary care clinics. JAMA 2004;291:2705-12.  Olson SH, Mignone L, Nakraseive C, Caputo TA, Barakat RR, Harlap S. Symptoms of ovarian cancer. Obstet Gynecol 2001;98:212-7.  Rossing MA, Wicklund KG, Cushing-Haugen KL, Weiss NS. Predictive value of symptoms for early detection of ovarian cancer. J Natl Cancer Inst 2010;102:222-9.  Lurie G, Wilkens LR, Thompson PJ, Matsuno RK, Carney ME, Goodman MT.
Age, Caucasian race, ethnicity (especially Ashkenazi Jewish heritage), living in an industrialized country, and a history of endometriosis are other factors predisposing to ovarian cancer 25. In addition, several factors, particularly multiparity, oral contraceptive use, breastfeeding and tubal ligation, have been linked with a decreased incidence of ovarian cancer and are therefore believed to be protective against developing ovarian cancer 102, 103. Protective Factors Hysterectomy Tubal Ligation Multiparity Lactation Oral Contraceptive use Risk Factors Age Caucasian race Early menarche Ethnicity (Ashkenazi Jewish, Icelandic, Hungarian) Family history Fertility drug use Hormone replacement therapy Late menopause Nulliparity Personal history of breast cancer Residence in North America and Northern Europe Talc Endometriosis Table 2.
Use of yeast-secreted in vivo biotinylated recombinant antibodies (Biobodies) in bead-based ELISA. Clin Cancer Res 2008;14:2647-55.  Scholler N, Gross JA, Garvik B, et al. Use of cancer-specific yeast-secreted in vivo biotinylated recombinant antibodies for serum biomarker discovery. J Transl Med 2008;6:41. 34 Ovarian Cancer – Clinical and Therapeutic Perspectives  Liu B, Nash J, Runowicz C, Swede H, Stevens R, Li Z. Ovarian cancer immunotherapy: opportunities, progresses and challenges. J Hematol Oncol 2010;3:7.
Ovarian Cancer -Clinical Therapeutic Perspectives by Samir A. Farghaly