Download e-book for kindle: Organogenesis in Development by Peter Koopman (Eds.)

By Peter Koopman (Eds.)

ISBN-10: 0123809126

ISBN-13: 9780123809124

Figuring out organogenesis is critical to present efforts to direct stem cellphone differentiation and serve as within the context of a posh organ. Defects in organogenesis are usually the foremost manifestations of human genetic ailment syndromes. This quantity describes the advance of 10 significant organ structures, reviewed by means of specialists in each one, to supply an updated review for researchers inside and out of doors the sector, scholars, lecturers and clinicians.   Summarizes the major morphological and mobile occasions Emphasizes updated study when it comes to molecular keep an eye on mechanisms attracts on quite a number version vertebrates and modern experimental ways, together with classes learnt from human developmental affliction Distils universal subject matters and adjustments for comparative reviews Highlights key final questions and units the time table for destiny learn

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311, 297–310. , Webb, S. and Henderson, D. J. (2009). Dual role for neural crest cells during outflow tract septation in the neural crest-deficient mutant Splotch(2H). J. Anat. 214, 245–257. Brown, C. , Lu, M. , Webber, A. , Raper, J. A. and Epstein, J. A. (2001). PlexinA2 and semaphorin signaling during cardiac neural crest development. Development 128, 3071–3080. Brown, C. , Wenning, J. , Lu, M. , Epstein, D. , Meyers, E. N. and Epstein, J. A. (2004). Cre-mediated excision of fgf8 in the tbx1 expression domain reveals a critical role for fgf8 in cardiovascular development in the mouse.

Yelon, D. and Bakkers, J. (2009). Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart. Development 136, 1633–1641. , Verzi, M. , Anderson, J. -M. and Black, B. L. (2004). Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development. Development 131, 3931–3942. Dyer, L. and Kirby, M. (2009). Sonic hedgehog maintains proliferation in secondary heart field progenitors and is required for normal arterial pole formation.

Meyers, E. N. and Epstein, J. A. (2004). Cre-mediated excision of fgf8 in the tbx1 expression domain reveals a critical role for fgf8 in cardiovascular development in the mouse. Dev. Biol. 267, 190–202. Bruneau, B. G. (2008). The developmental genetics of congenital heart disease. Nature 451, 943–948. , Roberts, D. , Huang, P. , Domian, I. J. and Chien, K. R. (2009). Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages. Nature 460, 113–117. , Meilhac, S. and Zaffran, S.

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Organogenesis in Development by Peter Koopman (Eds.)

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