By Josef Neu
This fascinating new reference brings you information regarding the main arguable gastroenterology and nutrients demanding situations you face on your perform. The booklet hopefully tackles those matters and provides professional suggestion at the most up-to-date diagnostic and remedy concepts utilizing evidence-based medication anyplace attainable. It supplies the most recent details you must continue velocity with the fast moving, dynamic surroundings of neonatology.Addresses debatable issues head on, so that you can come to a decision tips to deal with those tricky perform issues.Serves because the bridge among the newest state-of-the-art study and its program to scientific perform. Assembles a world-class workforce of neonatologists, representing the real leaders of the uniqueness, to make sure the main authoritative content material to be had.
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Extra info for Neonatology Questions and Controversies Series: Gastroenterology and Nutrition
Hirschsprung’s Disease The most intensively studied aspect of the development of the large intestine is the mechanism of Hirschsprung’s disease (HSCR), which is characterized by the absence of parasympathetic intrinsic ganglion cells in both the submucosal (Meissner’s) and myenteric (Auerbach’s) plexus of the hindgut. The disorder is 20 1 caused by failure of vagal neural crest cells to migrate into the distal end of the intestine and represents the most common form of congenital bowel obstruction.
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Roberts DJ, Johnson Rl, Burke AC, et al. Sonic hedgehog is an endodermal signal inducing bmp-4 and hox genes during induction and regionalization of the chick hindgut. Development 1995; 121:3163–3174. 30. Roberts DJ, Smith DM, Goff DJ, Tabin CJ. Epithelial-mesenchymal signaling during the regionalization of the chick gut. Development Suppl 1998; 125:2791–2801. 31. Motoyama J, Liu J, Mo R, et al. Essential function of gli2 and gli3 in the formation of lung, trachea and oesophagus. Nat Genet 1998; 20:54–57.
Neonatology Questions and Controversies Series: Gastroenterology and Nutrition by Josef Neu