By Günther Schneider M.D., Luigi Grazioli M.D., Sanjay Saini M.D. (auth.), Günther Schneider M.D., Luigi Grazioli M.D., Sanjay Saini M.D. (eds.)
Due to the most recent advancements in magnetic resonance imaging for the review of liver pathology, a moment, thoroughly revised and enlarged version of this publication used to be felt worthwhile – regardless of purely 3 years having elapsed because the first edition.
All chapters from the 1st version were revised and enriched with extra illustrations and data. New chapters were further masking vital and hugely proper subject matters, between which imaging of pseudolesions, imaging of neoplastic illnesses in pediatric matters, imaging of bile ducts, MR angiography and imaging pre and publish liver transplantation.
Particular consciousness has been paid to the differential use of distinction brokers with emphasis put on the authors’ huge adventure of MR imaging of focal liver lesions utilizing assorted distinction brokers. the varied mechanisms of motion of all MR distinction brokers acceptable for liver imaging are defined intimately and comparative examples are provided.
As was once the case with the 1st variation, this booklet will end up necessary to radiologists wishing to additional extend or consolidate their regimen method of MR imaging of the liver.
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Additional resources for MRI of the Liver: Imaging Techniques, Contrast Enhancement, Differential Diagnosis
The histology of this lesion was shown to be comparable with that of mycobacterial pseudotumors of the lymph nodes, spleen and lung in a patient infected with HIV . From this observation it was concluded that the immune system plays an important role in the pathogenesis of this kind of mass lesion. Additionally, electron microscopy may demonstrate intracellular bacilliform organisms. Molecular analysis of DNA fragments was able to identify Pseudomonas sub-populations that were not known to be infectious in humans.
Macroscopically, the tumors have a lobular appearance with fibrous septa and a central scar, which, in contrast to that in FNH, is a true scar. FLC lesions have a distinctive microscopic pattern and are composed of eosinophilic, malignant hepatocytes containing prominent nuclei. FLCs express hepatic as well as biliary keratin. The fibrous component accounts for 50% of the tumoral mass Fig. 19. Histology of a fibrolamellar carcinoma demonstrating tumor cells separated by characteristic parallel lamellae of coarse, ropy collagen Fig.
Most of these infantile mesenchymal tumors are found during the first six months of life, and there seems to be a slight female predominance . Common symptoms include hepatomegaly or a palpable mass, sometimes together with diminished growth or high-output cardiac failure caused by shunting. Rupture, thrombocytopenia and hypofibrinogenemia may occur on rare occasions. Surgical intervention may be avoided if no lifethreatening complications appear, as the tumor tends to regress gradually. Therapeutic strategies may consist of steroids, chemo- or radiotherapy, embolization or resection.
MRI of the Liver: Imaging Techniques, Contrast Enhancement, Differential Diagnosis by Günther Schneider M.D., Luigi Grazioli M.D., Sanjay Saini M.D. (auth.), Günther Schneider M.D., Luigi Grazioli M.D., Sanjay Saini M.D. (eds.)