Ross L. Cagan and Thomas A. Reh (Eds.)'s Invertebrate and Vertebrate Eye Development PDF

By Ross L. Cagan and Thomas A. Reh (Eds.)

ISBN-10: 0123850444

ISBN-13: 9780123850447

Imaginative and prescient is our fundamental sensory modality and we're certainly curious as to how the visible method assembles. The visible method is in lots of methods remarkably easy, a repeating assemblage of neurons and aid cells that parse the field of vision via precision and redundancy. via this simplicity the attention has usually led the best way in our exploration of ways an organ is assembled. Eye improvement has accordingly lengthy been a favourite for exploring mechanisms of phone destiny selection, patterning and cellphone signaling. This quantity, that's a part of the present subject matters in Developmental Biology sequence, highlights the outstanding advances during the last two decades Contributions from researchers who're lively in opting for new paradigms to discover evaluation of our present nation of information Chapters written via authors with a brand new iteration strategy that takes a extra structures method of deciding on components and higher defines mobilephone subtypes

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Extra resources for Invertebrate and Vertebrate Eye Development

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123, 264–275. , and Ready, D. F. (1987b). Neuronal differentiation in the Drosophila ommatidium. Dev. Biol. 120, 366–376. Tootle, T. , Silver, S. , Davies, E. , Latek, R. , Mills, I. , Selengut, J. , Parlikar, B. , and Rebay, I. (2003). The transcription factor Eyes absent is a protein tyrosine phosphatase. Nature 426, 299–302. Treisman, J. , and Rubin, G. M. (1995). Wingless inhibits morphogenetic furrow movement in the Drosophila eye disc. Development 121, 3519–3527. Voas, M. , and Rebay, I. (2004).

Bessarab, D. , Kuo, Y. , Beckendorf, S. , and Sun, Y. H. (2003). Two Pax genes, eye gone and eyeless, act cooperatively in promoting Drosophila eye development. Development 130, 2939–2951. Jaw, T. , You, L. , Knoepfler, P. , Yao, L. , Pai, C. , Tang, C. , Chang, L. , Kamps, M. , and Sun, Y. H. (2000). Direct interaction of two homeoproteins, homothorax and extradenticle, is essential for EXD nuclear localization and function. Mech. Dev. 91, 279–291. , and Gruss, P. (1998). Molecular regulators involved in vertebrate eye development.

In addition to Emc holding the furrow to a sustainable pace across the disk, the Wingless (Wg) signaling pathway prevents pattern formation from initiating inappropriately from the lateral margins of the epithelium. Wg is expressed at the margins and its loss leads to the initiation of ectopic morphogenetic furrows (Ma and Moses, 1995; Treisman and Rubin, 1995). Within the morphogenetic furrow itself (Zone D), cells are arrested in the G1 phase of the cell cycle. As they transition to positions behind the furrow, a subset of cells will exit the cell cycle and begin to initiate their development as the first five cells of the ommatidium (R8, R2, R5, R3, and R4) while the remainder will undergo one last round of synchronous cell division which will in turn lead to the production of the remaining photoreceptor neurons (R1, R6, and R7), the nonneuronal cone and pigment cells, as well as the cells of the bristle complex (Wolff and Ready, 1991).

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Invertebrate and Vertebrate Eye Development by Ross L. Cagan and Thomas A. Reh (Eds.)


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