By Tobias Fischer, Martin Langanke, Paul Marschall, Susanne Michl
In 2009 the college drugs Greifswald introduced the “Greifswald method of Individualized drugs” (GANI_MED) to enforce biomarker-based individualized diagnostic and healing options in scientific settings. Individualized drugs (IM) has led not just to controversies approximately its potentials, but additionally approximately its societal, moral and health and wellbeing fiscal implications. This anthology focusses on those parts and contains – subsequent to scientific examples illustrating how the built-in research of biomarkers results in major development of healing results for a subgroup of sufferers – chapters concerning the definition, heritage and epistemology of IM. also there's a specialise in conceptual philosophical questions in addition to demanding situations for utilized learn ethics (informed consent technique, the IT-based consent administration and the dealing with of incidental findings). eventually it will pay consciousness to wellbeing and fitness financial features. the probabilities of IM to start up a paradigm shift within the German well-being care provision are investigated. in addition, it really is requested no matter if the G-DRG procedure is prepared for the implementation of such techniques into scientific routine.
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Additional info for Individualized Medicine: Ethical, Economical and Historical Perspectives
Combinations has been a part of health care routine for a longer time. Relevant examples, picked up several times in the literature about Individualized or Personalized Medicine, are Herceptin or Tamoxifen, two drugs which are successfully being used against mamma carcinoma. , it is already standard that the drug is only prescribed, if a test showed beforehand that the tumor has certain molecular biological characteristics, which hint at a successful response to the drug. In the light of such cases, it can be said that: The oncological treatment of certain tumor diseases is a case of IM in the sense of the definition above.
Philosophy” does not mean the academic subject, of course, 2 The Meaning of “Individualized Medicine”: A Terminological … 17 but rather—in a figurative sense—a “(basic) orientation”, “background concept”, “guiding principle”, “trend”, “development” (the authors use the expression “development” themselves for reasons of explanation), maybe “vision” also, in any case something abstract, which begins to shape and change health care on the level of terms, concepts and ideas. The explanation by Costigliola et al.
2012b: Personalized (stratified) medicine is a new and important approach of the modern medical research. In the course of this concept, medical solutions shall be found which are specifically tailored for the need and circumstances of individual patients or certain patient groups. (Langanke et al. 302) If “IM” or “PM” is included in the generic terms “medical line of research” or “medial research approach” as in the cited explanations, it has to be clarified what “line of research” or “research approach” means.
Individualized Medicine: Ethical, Economical and Historical Perspectives by Tobias Fischer, Martin Langanke, Paul Marschall, Susanne Michl