Download PDF by Kiyokazu Morioka Ph.D. (auth.): Hair Follicle: Differentiation Under the Electron Microscope

By Kiyokazu Morioka Ph.D. (auth.)

ISBN-10: 4431224297

ISBN-13: 9784431224297

ISBN-10: 4431271791

ISBN-13: 9784431271796

Each and each hair is far greater than simply the seen shaft—there also are linked advanced sheath constructions of epidermal and dermal foundation. within the hair follicle, cells suffer quite a few differentiation techniques, as a rule reckoning on their layers and positions therein, and electron microscopy unearths a truly complicated structure. The constitution of a specific layer, comparable to Henle’s layer of the interior root sheath, isn't really uniform. really, cells tremendously swap in the course of the process differentiation. via easily evaluating electron micrographs of cells of a layer at various levels of differentiation, one could rarely realize them as belonging to an analogous layer. As readers will see, this publication comprises many remarkable electron mic- graphs, from low-magni?cation panoramic perspectives for orientation to hello- strength perspectives displaying ultrastructural aspect. Captions and schematic drawings also are very useful in “reading” electron micrographs and - derstanding the structural element. during this means, Dr. Morioka has succeeded in dissecting the complicated hair follicle on the ultrastructural level.

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Additional resources for Hair Follicle: Differentiation Under the Electron Microscope - An Atlas

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Cx, hair cortex; Ce, hair cuticle; n, nucleus; Ci, cuticle of inner root sheath. A A cortex cell in the early stage of the keratinization. B Thick bundles of tonofilaments are formed in a cortex cell. C The cytoplasm of a cortex cell is about to be filled with tonofilament bundles. D A cuticle cell before keratinization. E, F, G Progress of the keratinization of cuticle cells and concomitant morphological change of their nuclei. Samples were obtained from the dorsal skin of day 7 rats except C, which was from face skin of a day 2 rat.

Regrettably, parts B and D show knife marks. Samples were obtained from the dorsal skin of day 7 (A, C) or day 14 (B, D) rats. Bars A, B 1 mm; C, D 500 nm Keratin Filament Bundles Fig. 4. 51 52 3. Hair Cortex and Hair Cuticle Fig. 5. Fine structures of the bundles. A Fingerprint-like staining pattern characteristic of keratin filament in the cortex cell. B Cross section of keratin fibers in the cortex cell. Samples were obtained from the dorsal skin (A) or facial skin (B) of day 2 rats. Bars 200 nm Keratin Filament Bundles The structure of the bundles is detailed in Fig.

11). The process thereafter deviates from that of typical apoptosis. The chromatin swells and diffuses evenly in the nucleoplasm in later stages, resulting in a structure-less nucleus (Fig. 12). Neither crescent shaping of chromatin nor fragmentation of chromatin or of the nucleus is observed. According to the original study, apoptosis occurs sporadically [20]; here, in contrast, the pattern of the death of medulla cells occurs contiguously in the central tract of the hair. In view of its morphological features, I consider the death of these cells to resemble that of embryonic erythroid cells [22] rather than typical apoptotic cell death.

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Hair Follicle: Differentiation Under the Electron Microscope - An Atlas by Kiyokazu Morioka Ph.D. (auth.)


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