By Eric Engel, Stylianos E. Antonarakis
Eric Engel and Stylianos Antonarakis have written the main authoritative and important reference on molecular and medical facets of uniparental disomy (UPD) and genomic imprinting to this point. Genomic Imprinting and Uniparental Disomy in drugs good points entire overviews of a mess of genetic problems associated with UPD, with a powerful emphasis on medical results. This ebook will offer readers with the instruments essential to establish and deal with ailments linked to nontraditional chromosomal inheritance.
Genomic Imprinting and Uniparental Disomy in medication beneficial properties convenient tables summarizing medical phenotypes and chromosomal involvement in UPD, in addition to transparent illustrations on imprinting mechanisms and diagnostic checking out. This authoritative, thoroughly up to date useful reference can be helpful for any scientific geneticist, genetic counselor, health professional, or researcher encountering sufferers with such problems or learning complicated ailment mechanisms.
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Extra resources for Genomic Imprinting and Uniparental Disomy in Medicine
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A, B, C, and D depict the four different alleles of locus X on the long arm of the chromosomal pair shown next to the symbol of each individual. An image of the polymorphic alleles after gel electrophoresis and autoradiography is shown on the right panel. For the interpretation of the results of the analysis, see the text. The detection of the polymorphic alleles of a given locus can be performed using numerous laboratory techniques (Dean, 1995). , 1977); all for SNPs. For the SSRs, the method used is PCR and acrylamide gel electrophoresis for fragment size discrimination that could be done either manually or using the automated nucleotide sequencers.
Genomic Imprinting and Uniparental Disomy in Medicine by Eric Engel, Stylianos E. Antonarakis