By Qihui Jim Zhai, Philip T. Cagle
Frozen sections are played whereas a sufferer is present process surgical procedure as a foundation for making a right away prognosis that might influence therapy judgements. Frozen part analysis is usually a hugely challenging state of affairs for the pathologist who needs to render a prognosis fast for the sufferer and medical professional. The Frozen part Library sequence will supply concise, easy, website particular handbooks which are good illustrated and spotlight the pitfalls, artifacts and differential prognosis concerns that come up within the moved quickly frozen part state of affairs. Qihui "Jim" Zhai, MD, FCAP, is Professor of Pathology, college of Cincinnati, Cincinnati, OH. he's additionally Attending Pathologist at larger Cincinnati Pathologists, Inc., Cininnati, OH.
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Additional info for Frozen Section Library: Head and Neck
42 Frozen Section Library: Head and Neck Fig. 51 PLGA: Perineural invasion is very helpful establishing a diagno sis of malignancy, since the cytology for this entity is usually bland. The pattern is that of an onion ring with tumor cells surrounding the nerve in a laminated manner. Fig. 52 Myoepithelial carcinoma: Low power picture demonstrates an infiltrating tumor growth border, an important malignant diagnostic feature. salivary glands 43 Fig. 53 Myoepithelial carcinoma: Tumor is composed of spindle and plasmacytoid myoepithelial cells with marked cytologic atypia and mitotic figures.
Here are some typical gross features of the most common tumors in salivary gland (Figs. 73): • A well-circumscribed tumor with cartilaginous appearance located in the parotid gland has a high likelihood of being a PA. • An infiltrative tumor with a fleshy appearance is highly sugges tive of a malignant tumor. • A cystic lesion with daughter satellites should remind us of a mucoepidermoid carcinoma. • A cystic brown to tan color lesion with papillae and yellowish fluid is highly suggestive of a Warthin tumor.
11 PA: Higher power view of the typical PA histology. 22 Frozen Section Library: Head and Neck Fig. 12 PA with tissue infarction/necrosis and reactive atypia. Fig. 13 PA with marked reactive change and a cluster of bland metaplastic s quamous cells. salivary glands 23 Fig. 14 The overview demonstrates PA features at the right upper periphery and the infarction as well as the reactive changes in the center. Fig. 15 A minor salivary gland PA is well demarcated, but not encap sulated. 24 Frozen Section Library: Head and Neck Fig.
Frozen Section Library: Head and Neck by Qihui Jim Zhai, Philip T. Cagle