Download e-book for iPad: Dystonia (World Federation of Neurology Seminars in Clinical by Theodore L. Munsat, Joseph Jankovic

By Theodore L. Munsat, Joseph Jankovic

ISBN-10: 1888799870

ISBN-13: 9781888799873

This quantity is the 3rd in a chain built less than the auspices of the realm Federation of Neurology to satisfy the desires of neurologists who needs to perform drugs with out the various merits which are usually taken with no consideration within the industrialized international. it's specific to neurologists working towards in low-resource environments and people who desire to perform in your price range neurology, and addresses concerns very important for neurologists in constructing international locations that aren't coated in normal textbooks. The sequence will replace the reader in at present accredited diagnostic and administration perform. fabric is gifted in a straight forward, interactive demeanour, with ample case material.Dystonia is the 3rd most typical stream illness after Parkinson's affliction and Tremor. it's a neurologic sickness characterised through involuntary, sustained, patterned and infrequently repetitive muscle contractions of opposing muscle mass that strength elements of the physique into irregular and infrequently painful postures. Dystonia can impact any a part of the physique and whereas now not deadly, it's a continual and debilitating ailment. handling dystonic stipulations will be tough in constructing international locations the place there are restricted diagnostic and healing assets. using botulinum toxin, thought of the therapy of selection for plenty of focal or segmental dystonias, is mentioned in regard to its fee effectiveness within the surroundings of restricted assets. Dystonia presents a realistic evaluation of the disease that emphasizes affordable assessment and therapy and recommendation on easy methods to practice the present wisdom in medical perform. this article is going to be a welcome variation to the overseas literature at the topic.

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Extra resources for Dystonia (World Federation of Neurology Seminars in Clinical Neurology, Volume 3)

Sample text

Cardoso F, Jankovic J. Blepharospasm. ) Handbook of Dystonia. ; 1995:129–141. Chan J, Brin MF, Fahn S. Idiopathic CD: clinical characteristics. Mov Disord 1991;6:119–126. Comella CL, Jankovic J, Brin MF. Use of botulinum toxin type A in the treatment of cervical dystonia. Neurology 2000;55(12 suppl 5):S15–S21. Dutton JJ, Buckley EG. Botulinum toxin in the management of blepharospasm. Arch Neurol 1986;43:380–382. Jankovic J, Ford J. Blepharospasm and orofacial-cervical dystonia: clinical and pharmacological findings in 100 patients.

Neuroleptic Drugs Classic neuroleptics have been employed to treat severe dystonia. Their use is still controversial, because some studies have reported efficacy (improvement of 11%–30%), while others have not. However, side effects of classic neuroleptics (such as sedation, apathy, nausea, orthostatic hypotension, insomnia, akathisia, and confusion) and the risk of producing tardive dyskinesias now greatly limit their usage. Tetrabenazine is a presynaptic monoamine-depleting drug that also blocks postsynaptic dopamine receptors.

Arch Phys Med Rehabil 1979;60:155–158. Jankovic J, Fahn S. Dystonic disorders. ) Parkinson’s Disease and Movement Disorders. 3rd ed. Baltimore: Williams & Wilkins; 1998. Jankovic J. Post-traumatic movement disorders: central and peripheral mechanisms. Neurology 1994;44:2006–2014. Karp BI, Cole RA, Cohen LG, Grill S, Lou JS, Hallett M. Long-term botulinum toxin treatment of focal hand dystonia. Neurology 1994;44(1):70–76. Molloy FM, Shill HA, Kaelin-Lang A, Karp BI. Accuracy of muscle localization without EMG: implications for treatment of limb dystonia.

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Dystonia (World Federation of Neurology Seminars in Clinical Neurology, Volume 3) by Theodore L. Munsat, Joseph Jankovic


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