By Joachim Weis, Markus Horneber
Cancer-related fatigue (CrF) is more and more famous as a signiﬁcant challenge for sufferers with melanoma in any respect levels, together with these present process remedy and in remission. in reality, experiences have proven that CrF reasons sufferers extra misery than soreness, nausea, or vomiting and but fatigue remains to be usually undertreated and barely studied. besides the fact that, numerous new remedies akin to are being investigated to figure out the best how you can deal with this debilitating symptom and enhance sufferer caliber of existence. Cancer-Related Fatigue will supply a concise evaluate of this , with an evidence-based dialogue of analysis, remedy, and long term management.
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Extra info for Cancer-Related Fatigue
48. Blaney J, Lowe-Strong A, Rankin J, Campbell A, Allen J, Gracey J. The cancer rehabilitation journey: barriers to and facilitators of exercise among patients with cancer-related fatigue. Phys Ther. 2010;90: 1135–47. 1 Introduction Pharmacological treatment of cancer-related fatigue (CrF) is generally based on addressing symptoms and reducing intensifying factors such as anemia, malnutrition, sleep, and endocrine disorders, as well as impacting possible pathophysiological factors such as changes in the serotonergic system of the central nervous system (CNS) and dysregulation of inflammatory cytokines.
36 3 Diagnosis and Assessment 22. Pearson RG, Byars GE. The development and validation of a checklist measuring subjective fatigue. Air University, School of Aviation Medicine, US Air Force, Randolph Air Force Base, Texas, Document No. 56115;1956. 23. Chalder T, Berelowitz G, Pawlikowska T, et al. Development of a fatigue scale. J Psychosom Res. 1993;37:147–53. 24. Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology.
CBT in CrF takes into account the thoughts and functional behaviors relevant to the syndrome and focuses on the individual and their pattern of psychological factors . CBT is generally used post-treatment, but may be also used for patients with CrF still undergoing chemotherapy . Based on existing literature and experience in clinical practice, CBT is generally used to address the following factors: • • • • • • coping with the experience of cancer ; fear of disease recurrence [10, 20]; dysfunctional thoughts and beliefs regarding fatigue [21, 22]; sleep dysregulation [23, 24]; activity dysregulation [10, 20, 24]; and low level of social support/negative social interactions .
Cancer-Related Fatigue by Joachim Weis, Markus Horneber