By Dan Longo, Bruce A. Chabner
Updated to incorporate the most recent medicines and people presently in improvement, Cancer Chemotherapy and Biotherapy, 5th Edition is a finished reference at the preclinical and medical pharmacology of anticancer brokers. geared up by means of drug category, the booklet offers the most recent details on all medicinal drugs and organic agents—their mechanisms of motion, interactions with different brokers, toxicities, negative effects, and mechanisms of resistance. Chapters emphasize pharmacology and mechanisms of motion on the molecular and mobile degrees, via scientific job and toxicity, either acute and not on time. The authors clarify the explanation to be used of substances in particular schedules and mixtures and supply guidance for dose adjustment particularly situations.
This edition's creation contains well timed info on common concepts for drug utilization, the technology of drug discovery and improvement, monetary and regulatory features of melanoma drug improvement, and rules of pharmacokinetics. 8 new chapters were extra and greater than twenty were considerably revised.
A better half web site contains the absolutely searchable textual content and a picture bank.
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Extra info for Cancer Chemotherapy and Biotherapy: Principles and Practice (Chabner, Cancer Chemotherapy and Biotherapy)
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Clinical pharmacokinetics of suramin in patients with HTLV-III/LAV infection. J Clin Pharmacol 1986;26:22. 35. Donehower RC, Karp JE, Burke PJ. Pharmacology and toxicity of high-dose cytarabine by 72-hour continuous infusion. Cancer Treat Rep 1986;70:1059. 36. Oates J, Wilkinson G. Principles of drug therapy. , eds. Harrison's principles of internal medicine, 8th ed. New York: McGraw-Hill, 1977:334–346. 37. Gibaldi M, Perrier D. Pharmacokinetics, 2nd ed. New York: Marcel Dekker, 1982. 38. McManus ME, Monks A, Collins JM, et al.
Cancer Chemotherapy and Biotherapy: Principles and Practice (Chabner, Cancer Chemotherapy and Biotherapy) by Dan Longo, Bruce A. Chabner