By Hans-Georg Joost, Hadi Al-Hasani, Annette Schürmann
Detailing the newest protocols for getting to know animal versions of diabetes, in particular resistant teams of rodents corresponding to the NOD mouse, and together with specialist recommendation on implementation, this can be a worthy new quantity within the tools in Molecular Biology sequence.
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This tunnel allows easy access to the food drawer, while its small size discourages rodents from nesting or sleeping inside. It prevents spilled food from entering the cage and contaminating the urine collection. 4. Food drawer: Constructed of transparent acryl. Slides out for easy filling with slurries, liquids or powders, without disturbing the animal. 5. Water bottle holder: Constructed of transparent acryl. Located outside cage. 6. Water bottle: Constructed of acryl. Fig. 1. Individual mouse metabolic cage (Courtesy of R.
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J Immunol 136: 148–151 27. Bortell R, Kanaitsuka T, Stevens LA et al (1999) The RT6 (Art2) family of ADPribosyltransferases in rat and mouse. Mol Cell Biochem 193:61–68 28. Bortell R, Waite DJ, Whalen BJ et al (2001) Levels of Art2+ cells but not soluble Art2 protein correlate with expression of autoimmune diabetes in the BB rat. Autoimmunity 33:199–211 29. Gold DP, Bellgrau D (1991) Identification of a limited T-cell receptor beta chain variable region repertoire associated with diabetes in the BB rat.
Animal Models in Diabetes Research by Hans-Georg Joost, Hadi Al-Hasani, Annette Schürmann