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Embryonic connective-tissue cells of the mesoMembrane may become blast develop membrane. bone directly or cartilage may be deposited, which cartilage by the process of ossification is changed into bone. The tissue which is eventually to become bone contains cellular elements which evolve into osteoOsteoblasts exist in the blasts, or bone-forming cells. connective tissues which become bone by intramembranous ossification, and in the deeper layers of the tissue called perichondrium which invests cartilage and which becomes the osteogenetic layer of the periosteum.

The term skeleton is, therefore, In the human confined to the endoskeleton, and this is divisible into an axial part, which includes that of the head and trunk, and an appendicular part, which comprises that of the limbs. In the skeleton of the adult there are 206 distinct bones, as follows: f Vertebral Axial Skeleton J j column Skull 26 22 Hyoid bone and sternum 25 libs iRil; Appendicular f Skeleton \ Upper limbs Lower limbs Auditory ossicles 1 — 74 64 62 — 126 6 Total 206 The patellae are included in this enumeration, but the smaller sesamoid bones are not reckoned.

Vessels These are also seen at the junctions of the lamellae (Fig. 13). clasts of the primitive The osteo- marrow apply themselves to the walls of the canals and absorb the osseous tissue until a comparatively large and regular canal is formed, and within this canal the osteoblasts secrete successive concentric layers of bone until a small central canal alone remains which contains a little marrow and the vessels. This canal is the true Haversian canal. The concentric lamelke are the Haversian lamellae, between which the osteoblasts remain in their lacunae and radiating canFig.

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Anatomy, descriptive and applied. by H. Gray

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