By Richard L. Attanoos
Advances in Surgical Pathology: Mesothelioma, a quantity within the Advances in Surgical Pathology sequence, gains chapters on present and drawing close alterations within the box with an emphasis on sensible matters, fresh advancements, and rising concepts.
Created as a short evaluate, this quantity offers a concise, up to date evaluate of the pathological features of mesothelioma—emphasizing the histologic correlation, scientific administration, and therapy of the disease. well timed content material positive aspects comprise acceptance of precursor mesothelial lesions, the position of molecular biology within the prognosis and analysis of mesothelioma, the interface among the clinician and the surgical pathologist, and the criminal implications of attributing affliction beginning to asbestos and different components. The booklet offers a source for the periodic updates in wisdom required for day-by-day perform, for present credentialing, and for the self-assessment modules for recertification.
- Concise and sensible format offers a short evaluate of mesothelioma perfect for citizens, fellows, training pathologists, and clinicians.
- Core content material addresses mesothelioma analysis, WHO type, staging, imaging, biopsy, mimicking stipulations, immunohistochemistry, precise gene remedy, and the opportunity of stem mobilephone treatment.
- Focus on fresh advances and rising technologies is helping consultant readers’ medical care whilst treating sufferers with mesothelioma.
- Over one hundred ten full-color images enhance diagnostic accuracy.
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Extra resources for Advances in Surgical Pathology: Mesothelioma
RADIATION Ionizing radiation has been recognized as a human carcinogen and an established risk factor for several different types of cancer. These have included hematologic malignancies and solid tumors. In addition, there have been increasing reports of cases of pleural, pericardial, and peritoneal diffuse malignant mesothelioma that have been linked to therapeutic irradiation and thorium dioxide administration. 21 study, which followed non-Hodgkin lymphoma patients from 1973 to 2001, there was a significantly increased rate of diffuse malignant mesothelioma in patients treated with radiation compared with those which did not receive radiation.
Eur J Respir Dis 1982;63:87. 6. Dimitrov NV, McMahon S. Presentation, diagnostic methods, staging, and natural history of malignant mesothelioma. In: Antman KH, Aisner J, eds. Asbestos-Related Disease. Orlando, FL: Grune & Stratton; 1987:225–238. 7. Rusch VW. A proposed new international TNM staging system for malignant pleural mesothelioma. From the International Mesothelioma Interest Group. Chest 1995;108:1122–1128. AJCC. Cancer Staging Manual. 6th ed. New York, NY: Springer-Verlag; 2002:180–181.
What is not known is whether there is a clinical difference between contrast-enhanced CT and contrast-enhanced MRI in predicting resectability. Dynamic contrast-enhanced-MRI (DCE-MRI) is the acquisition of sequential images during the passage of a contrast agent within a tissue of interest. Gadolinium contrast agents allow visualization of vasculature and can be used to assess vascular permeability. 27,28 Therefore, DCE-MRI potentially provides noninvasive characterization of antiangiogenic response of pleural diffuse (c) 2015 Wolters Kluwer.
Advances in Surgical Pathology: Mesothelioma by Richard L. Attanoos